Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205707 | 1.00 | MAPT (0.51) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2205704 | 1.00 | MAPT (0.51) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL5525558 | 0.90 | SMN1; SMN2 (0.49) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6484891 | 0.90 | SMN1; SMN2 (0.49) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL5525560 | 0.90 | SMN1; SMN2 (0.49) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL5694711 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1NPSR1POLBL3MBTL1 | |
| SCHEMBL14131630 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1NPSR1POLBL3MBTL1 | |
| SCHEMBL5694743 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1NPSR1POLBL3MBTL1 | |
| SCHEMBL12883157 | 0.86 | MAPT (0.45) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL26845457 | 0.86 | MAPT (0.45) | MAPTKMT2AMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | claimed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | claimed |
| CN-115260178-B | Synthetic method and application of pyridine skeleton NCN oxazoline ligand | 上海师范大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-117304027-A | Application of hydroxy aromatic aldehyde in photo-assisted catalysis of cis-isomerization of unsaturated organic matters | 四川大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-115260178-A | Synthesis method and application of pyridine-skeleton NCN oxazoline ligand | 上海师范大学 | 2022-11-01 | — | — | CN | disclosed |
| US-11446636-B2 | Jute stem-supported palladium-NPS and use as dip-catalysts for aqueous transfer hydrogenation | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-09-20 | — | — | US | disclosed |
| CN-109071446-B | Organic reaction in aqueous solution in the presence of hydroxyalkyl (alkyl) cellulose or alkylcellulose | 艾伯维德国有限责任两合公司 | 2022-06-21 | — | — | CN | disclosed |
| US-20220152587-A1 | JUTE STEM-SUPPORTED PALLADIUM-NPS AND USE AS DIP-CATALYSTS FOR AQUEOUS TRANSFER HYDROGENATION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-05-19 | — | — | US | disclosed |
| US-11312668-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | ABBVIE INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210017100-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | AbbVie Deutschland GmbH & Co. KG (DE) | 2021-01-21 | — | — | US | disclosed |
| US-10836688-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | ABBVIE INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-6465664-B1 | CATALYZED WITH A TRANSITION METAL CATALYST COMPOSED OF A COPPER COMPOUND AND AN ASYMMETRIC LIGAND, SUCH AS A PHOSPHINE, A NUCLEOPHILE AND A BASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-10-15 | — | — | US | disclosed |
| US-20020128486-A1 | Phosphinite-oxazolines and metal complexes | PFALTZ ANDREAS (CH) | 2002-09-12 | — | — | US | disclosed |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | SOLVIAS AG (CH) | 2002-05-23 | — | — | US | disclosed |
| EP-1191030-A2 | Phosphinite-oxazolines and metal complexes | Solvias AG (CH) | 2002-03-27 | — | — | EP | disclosed |
| EP-1149067-A1 | 7-ARYL-6(Z)HEPTATRIENOIC ACID RETINAMIDES AS APOPTOSIS INDUCING COMPOUNDS AND THEIR USE AS ANTI-CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| US-6310247-B1 | HAS APOPTOTIC ACTIVITY USEFUL FOR PROPHYLAXIS AND THERAPY OF CANCER | HOFFMANN-LA ROCHE INC. | 2001-10-30 | — | — | US | disclosed |
| WO-2001019761-A2 | ASYMMETRIC 1,4-REDUCTIONS OF AND 1,4-ADDITIONS TO ENOATES AND RELATED SYSTEMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-2000035856-A1 | 7-ARYL-6(Z)HEPTATRIENOIC ACID RETINAMIDES AS APOPTOSIS INDUCING COMPOUNDS AND THEIR USE AS ANTI-CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |
| US-4789756-A | REACTING ALKENYL AROMATIC WITH CARBON MONOXIDE AND ALCOHOL | SHELL OIL COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | XPA, MEP1A, EED | MAPT 4688/4885KMT2A 1689/4885MEN1 809/4885 |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | XPA, MEP1A, EED | MAPT 4688/4885KMT2A 1689/4885MEN1 809/4885 |
| US-20210017100-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | LIPA, ALG1, CEL | MAPT 3070/4885KMT2A 4694/4885MEN1 4302/4885 |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | OXER1, OXGR1, H1-4 | MAPT 4862/4885KMT2A 1894/4885MEN1 1515/4885 |
| US-10836688-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | LIPA, ALG1, CEL | MAPT 3070/4885KMT2A 4694/4885MEN1 4302/4885 |
| US-20020128486-A1 | Phosphinite-oxazolines and metal complexes | OXER1, OXGR1, H1-4 | MAPT 4862/4885KMT2A 1894/4885MEN1 1515/4885 |
| US-11312668-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | LIPA, ALG1, CEL | MAPT 3070/4885KMT2A 4694/4885MEN1 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.