Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.70 |
| ▸ | CA1 | P00915 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106254 | 1.00 | CA2 (0.70) | CA2CA1MAPK1MEN1ALDH1A1 | |
| SCHEMBL6920893 | 0.92 | CA2 (0.60) | CA2CA1MAPK1MMP1MMP2 | |
| SCHEMBL18376172 | 0.92 | CA2 (0.60) | CA2CA1MAPK1MMP1MMP2 | |
| SCHEMBL25090841 | 0.91 | CA2 (0.57) | CA2CA1MAPK1MMP1MMP2 | |
| SCHEMBL8257353 | 0.87 | CA2 (0.53) | CA2CA1MAPK1MMP1MMP2 | |
| SCHEMBL18643837 | 0.87 | HDAC7 (0.56) | CA2CA1MAPK1TSHRMMP1 | |
| SCHEMBL18664332 | 0.86 | HDAC7 (0.54) | CA2CA1MAPK1MEN1ALDH1A1 | |
| SCHEMBL18664295 | 0.86 | HDAC7 (0.54) | CA2CA1MAPK1MEN1ALDH1A1 | |
| SCHEMBL22276969 | 0.85 | CA2 (0.57) | CA2CA1MMP1MMP2MMP3 | |
| SCHEMBL12786227 | 0.85 | CA2 (0.57) | CA2CA1MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |