Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | MMP3 | P08254 | 11/20 | 0.53 |
| ▸ | MMP2 | P08253 | 9/20 | 0.53 |
| ▸ | MMP1 | P03956 | 9/20 | 0.53 |
| ▸ | MMP7 | P09237 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18376172 | 1.00 | CA2 (0.60) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL2106254 | 0.92 | CA2 (0.70) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL19135674 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL2482311 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL2483893 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL5326388 | 0.92 | CA2 (0.70) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL20987781 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL11515533 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL21664527 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 | |
| SCHEMBL2481778 | 0.92 | MMP3 (0.55) | CA2CA1MMP3MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009897-A1 | FUSED AMINODIHYDROPYRIMIDONE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD (JP) | 2011-01-27 | — | — | WO | disclosed |