Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.54 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21084000 | 0.82 | CYP11B2 (0.56) | CYP11B2TRPV4CYP11B1EGLN2AR | |
| SCHEMBL2751204 | 0.82 | ALDH1A1 (0.43) | CYP11B2CYP11B1ARESR1ESR2 | |
| SCHEMBL25299104 | 0.81 | CYP11B2 (0.63) | CYP11B2TRPV4CYP11B1CASP1AR | |
| SCHEMBL30510168 | 0.81 | CYP11B2 (0.63) | CYP11B2TRPV4CYP11B1CASP1AR | |
| SCHEMBL7280930 | 0.81 | CYP11B2 (0.54) | CYP11B2TRPV4CYP11B1CASP1EGLN2 | |
| SCHEMBL533972 | 0.77 | AHR (0.67) | ESR2AHR | |
| SCHEMBL5327983 | 0.77 | CYP11B2 (0.58) | CYP11B2TRPV4CYP11B1 | |
| SCHEMBL18666733 | 0.77 | CYP11B2 (0.50) | CYP11B2TRPV4CYP11B1CASP1EGLN2 | |
| Methane SCHEMBL8006386 | 0.75 | AHR (0.64) | ESR2AHR | |
| Hydrochloric Acid SCHEMBL8019894 | 0.75 | AHR (0.64) | ESR2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |