Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329826 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5361482 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5329160 | 0.83 | PTGDR2 (0.58) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5325062 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5325095 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5327925 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5330434 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5335478 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL14346596 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5325066 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |