Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333711 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5361482 | 0.83 | KDM4E (0.61) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5329826 | 0.82 | KDM4E (0.68) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5326593 | 0.81 | KDM4E (0.57) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5329981 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5327950 | 0.80 | ALDH1A1 (0.85) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5329160 | 0.80 | PTGDR2 (0.58) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5325095 | 0.79 | KDM4E (0.56) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL14346596 | 0.78 | KDM4E (0.56) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL5335478 | 0.78 | KDM4E (0.53) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |