Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328044 | 0.82 | GSR (0.40) | DPP7GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL25271579 | 0.80 | ARG1 (0.40) | DPP7GSRALDH1A1CYP2C19ALOX15 | |
| SCHEMBL5697664 | 0.73 | GRIA1 (0.36) | KDM4ETYRDOHHDPP7GRIA1 | |
| SCHEMBL5697663 | 0.73 | GRIA1 (0.36) | KDM4ETYRDOHHDPP7GRIA1 | |
| SCHEMBL6698414 | 0.70 | — | — | |
| SCHEMBL31690305 | 0.69 | GRIA1 (0.39) | KDM4ETYRDOHHGRIA1GRIA2 | |
| SCHEMBL31690312 | 0.69 | GSR (0.37) | KDM4ETYRDOHHGRIA1GRIA2 | |
| SCHEMBL5322480 | 0.68 | GRIA1 (0.41) | KDM4ETYRDOHHDPP7GRIA1 | |
| Hydrochloric Acid SCHEMBL6277263 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1PKM | |
| SCHEMBL2113300 | 0.67 | GLA (0.38) | KDM4ECYP1A2KMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | KDM4E 2053/4885TYR 522/4885DOHH 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.