Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326584 | 0.82 | ALDH1A1 (0.59) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A | |
| SCHEMBL2293693 | 0.79 | CACNA1C (0.69) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A | |
| SCHEMBL4271063 | 0.74 | CACNA2D1 (0.70) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A | |
| SCHEMBL4284632 | 0.73 | CACNA2D1 (0.67) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A | |
| SCHEMBL14399186 | 0.72 | ALDH1A1 (0.74) | KMT2AMEN1ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL5264907 | 0.71 | CACNA2D1 (1.00) | CACNA1CCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5324722 | 0.71 | TACR3 (0.58) | CACNA1CCACNA2D1CACNA1BCACNB1ALDH1A1 | |
| SCHEMBL5327864 | 0.71 | CACNA1B (0.52) | CACNA1CCACNA2D1CACNA1BCACNB1HTT | |
| SCHEMBL7425100 | 0.70 | CACNA2D1 (0.54) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A | |
| SCHEMBL7391005 | 0.70 | CACNA2D1 (0.54) | CACNA1CCACNA2D1CACNA1BCACNB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |