Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325737 | 0.84 | NPC1 (0.59) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14995962 | 0.83 | HPGD (0.73) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL12585020 | 0.78 | POLB (0.59) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5326701 | 0.77 | HTT (0.70) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL3662909 | 0.75 | SMN1; SMN2 (0.71) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL12326826 | 0.74 | KMT2A (0.62) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL660986 | 0.74 | KMT2A (0.62) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL13932527 | 0.74 | KMT2A (0.83) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5328968 | 0.74 | MEN1 (0.50) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13870219 | 0.73 | SLC13A5 (0.50) | ALDH1A1TDP1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |