SCHEMBL5326701

SCHEMBL5326701

Cc1ccc(CNC(=O)CCC(=O)O)cc1

nearest known ligand 0.81

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.70
ALDH1A1 P00352 4/20 0.62
TDP1 Q9NUW8 1/20 0.62
KMT2A Q03164 6/20 0.61
MEN1 O00255 4/20 0.61
SMN1; SMN2 Q16637 1/20 0.59
HPGD P15428 1/20 0.58
TPSAB1 Q15661 1/20 0.58
USP2 O75604 1/20 0.57
CYP2C19 P33261 1/20 0.57
LMNA P02545 1/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14344692 0.84 TPSAB1 (0.61) HTTALDH1A1TDP1KMT2AMEN1
SCHEMBL17335992 0.84 CYP3A4 (0.63) ALDH1A1TDP1KMT2AMEN1SMN1; SMN2
SCHEMBL93948 0.83 GAA (0.75) HTTALDH1A1TDP1KMT2AMEN1
SCHEMBL16205823 0.82 HTT (0.70) HTTALDH1A1KMT2AMEN1TPSAB1
SCHEMBL14679156 0.82 TPSAB1 (0.62) ALDH1A1KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL11887809 0.82 HTT (0.70) HTTALDH1A1KMT2AMEN1TPSAB1
SCHEMBL21887672 0.82 TPSAB1 (0.86) HTTALDH1A1KMT2AMEN1TPSAB1
SCHEMBL2453831 0.82 HTT (0.70) HTTALDH1A1TDP1KMT2AMEN1
SCHEMBL27892112 0.82 HTT (1.00) HTTALDH1A1KMT2AHPGDTPSAB1
SCHEMBL25046063 0.81 ALDH1A1 (0.71) HTTALDH1A1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362199-B2 Borazine-based resin, process for its production, borazine-based resin composition, insulating film and method for its formation HITACHI CHEMICAL CO., LTD. (JP) 2013-01-29 US disclosed
US-20110313122-A1 BORAZINE-BASED RESIN, PROCESS FOR ITS PRODUCTION, BORAZINE-BASED RESIN COMPOSITION, INSULATING FILM AND METHOD FOR ITS FORMATION MATSUTANI HIROSHI (JP) 2011-12-22 US disclosed
US-7625642-B2 Borazine-based resin, and method for production thereof, borazine based resin composition, insulating coating and method for formation thereof, and electronic parts having the insulating coating HITACHI CHEMICAL CO., LTD (JP) 2009-12-01 US disclosed
US-20090240017-A1 Borazine-based resin, process for its production, borazine-based resin composition, insulating film and method for its formation HITACHI CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
WO-2007142431-A1 NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2007-12-13 WO disclosed
EP-0461677-B1 Novel thiazolidine derivatives ONO PHARMACEUTICAL CO (JP) 1997-04-16 EP disclosed
EP-0280956-B1 THIAZOLIDINE DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 1992-10-21 EP disclosed
EP-0461677-A1 Novel thiazolidine derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1991-12-18 EP disclosed
US-4857537-A PREVENTING AMNESIA ONO PHARMACEUTICAL CO., LTD. (JP) 1989-08-15 US disclosed
EP-0280956-A1 Thiazolidine derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313122-A1 BORAZINE-BASED RESIN, PROCESS FOR ITS PRODUCTION, BORAZINE-BASED RESIN COMPOSITION, INSULATING FILM AND METHOD FOR ITS FORMATION GRIK5, GJA1, SLC9A5 HTT 3590/4885ALDH1A1 2955/4885TDP1 2647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.