SCHEMBL3662909

SCHEMBL3662909

Cc1ccc(CNC(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.71
LMNA P02545 2/20 0.65
NPC1 O15118 4/20 0.63
KMT2A Q03164 10/20 0.62
MEN1 O00255 8/20 0.62
RAB9A P51151 3/20 0.62
HPGD P15428 2/20 0.62
TP53 P04637 1/20 0.62
ALDH1A1 P00352 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
TSHR P16473 1/20 0.57
CYP2C19 P33261 1/20 0.57
KDM4E B2RXH2 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11533429 0.91 CYP2C9 (0.65) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL2730689 0.86 SMN1; SMN2 (0.85) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL5933202 0.84 SMN1; SMN2 (0.63) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL5932688 0.84 CYP1A2 (0.55) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL12466491 0.84 CYP1A2 (0.55) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL171709 0.84 KMT2A (0.66) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL8602062 0.84 CYP2C9 (0.59) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL13049648 0.84 SMN1; SMN2 (1.00) SMN1; SMN2NPC1KMT2AMEN1RAB9A
SCHEMBL28909751 0.83 NPC1 (0.69) SMN1; SMN2LMNANPC1KMT2AMEN1
SCHEMBL5933146 0.83 SMN1; SMN2 (0.61) SMN1; SMN2LMNANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139860-A2 DERIVATIVES OF THE AMINATED HYDROXYQUINOLINE CLASS FOR TREATING CANCERS Biopharmed Société à Responsabilité Limitée (FR) 2010-01-06 EP claimed
WO-2008135671-A2 DERIVATIVES OF THE AMINATED HYDROXYQUINOLINE CLASS FOR TREATING CANCERS BIOPHARMED Société à responsabilité limitée (FR) 2008-11-13 WO claimed
EP-4145995-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB Applied Technologies, LLC (US) 2023-03-15 EP disclosed
CN-114040912-A Compounds for the treatment of kinase-dependent disorders 埃克塞里艾克西斯公司 2022-02-11 CN disclosed
WO-2021226566-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB APPLIED TECHNOLOGIES, LLC (US) 2021-11-11 WO disclosed
EP-3709804-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB Applied Technologies, LLC (US) 2020-09-23 EP disclosed
CN-102300847-A PPAR agonist compositions and methods of use thereof 2011-12-28 CN disclosed
EP-2139860-A2 DERIVATIVES OF THE AMINATED HYDROXYQUINOLINE CLASS FOR TREATING CANCERS Biopharmed Société à Responsabilité Limitée (FR) 2010-01-06 EP disclosed
WO-2008135671-A2 DERIVATIVES OF THE AMINATED HYDROXYQUINOLINE CLASS FOR TREATING CANCERS BIOPHARMED Société à responsabilité limitée (FR) 2008-11-13 WO disclosed
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 US disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed
EP-0298419-A2 A protein partial degradation product, process for preparing it and its use Katayama Chemical Works Co., Ltd. (JP) 1989-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR SMN1; SMN2 3024/4885LMNA 1161/4885NPC1 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.