Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.60 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328036 | 0.89 | GRIK1 (0.60) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL21219821 | 0.85 | SLC7A5 (0.54) | GRIA2HDAC1HDAC8PTGS2CTNNB1 | |
| SCHEMBL5322017 | 0.85 | SLC7A5 (0.54) | GRIA2HDAC1HDAC8PTGS2CTNNB1 | |
| SCHEMBL29981560 | 0.85 | SLC7A5 (0.54) | GRIA2HDAC1HDAC8PTGS2CTNNB1 | |
| SCHEMBL31370039 | 0.85 | SLC7A5 (0.54) | GRIA2HDAC1HDAC8PTGS2CTNNB1 | |
| SCHEMBL31688793 | 0.81 | GRIK1 (0.65) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28617979 | 0.79 | GRIK1 (0.63) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28617978 | 0.79 | GRIK1 (0.63) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL31369576 | 0.78 | PTGS2 (0.58) | GRIA2PTGS2ENPP2USP2ALOX15 | |
| SCHEMBL6263512 | 0.77 | HDAC1 (0.56) | HDAC1HDAC8CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | GRIK1 4162/4885GRIA1 3993/4885GRIA2 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.