Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327749 | 0.82 | PPARA (0.45) | TRPV1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5327164 | 0.81 | PPARA (0.54) | NPC1RAB9ATRPV1MEN1MAPT | |
| SCHEMBL5328303 | 0.78 | NPC1 (0.51) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL5327149 | 0.74 | PPARA (0.48) | MEN1MAPTKMT2ALMNAPPARA | |
| SCHEMBL3371243 | 0.73 | PPARA (0.64) | MEN1MAPTKMT2APPARAPPARG | |
| SCHEMBL5324710 | 0.73 | PPARA (0.47) | MEN1MAPTKMT2ALMNAPPARA | |
| SCHEMBL11558127 | 0.73 | PPARA (0.55) | MEN1MAPTKMT2APPARAPPARG | |
| SCHEMBL11551303 | 0.72 | PPARA (0.68) | TRPV1MEN1MAPTKMT2APPARA | |
| SCHEMBL7519747 | 0.72 | MAPT (0.82) | NPC1RAB9ATRPV1MEN1MAPT | |
| SCHEMBL17270209 | 0.72 | ACKR3 (0.73) | NPC1RAB9AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |