Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327159 | 0.82 | NPC1 (0.49) | PPARAMEN1LMNAKMT2AGAA | |
| SCHEMBL5327752 | 0.82 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6558040 | 0.76 | ALDH1A1 (0.63) | PPARAALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5327149 | 0.73 | PPARA (0.48) | PPARAALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL27948244 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MEN1LMNAKMT2ATP53 | |
| SCHEMBL3371243 | 0.72 | PPARA (0.64) | PPARAALDH1A1MEN1KMT2APPARD | |
| SCHEMBL5324710 | 0.72 | PPARA (0.47) | PPARAALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11558127 | 0.71 | PPARA (0.55) | PPARAMEN1KMT2APPARDPPARG | |
| SCHEMBL6558005 | 0.69 | PPARA (0.69) | PPARAALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5359559 | 0.69 | PTPN1 (0.51) | PPARAMEN1LMNAKMT2APPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |