Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8435181 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7926706 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL532723 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9145494 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9146197 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8059663 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3261 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1331961 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1537736 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-222197696-U | Sieving device for producing tricalcium carbonate | 江苏晓春新材料有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-221776393-U | Storage device for storing tri-calcium carbonate | 江苏晓春新材料有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118489324-A | Rapid raw soil curing method and device for effectively improving soybean yield | 浙江省农业科学院 | 2024-08-16 | — | — | CN | claimed |
| CN-113912343-B | Building plastering mortar suitable for robot and preparation method thereof | 浙江建工新材料有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115159485-A | Preparation method of pure tricalcium phosphate | 连云港树人科创食品添加剂有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114477770-A | Phosphate microcrystalline glass and preparation method thereof | 方益琴 | 2022-05-13 | — | — | CN | claimed |
| CN-113912343-A | Building plastering mortar suitable for robot and preparation method thereof | 浙江建工新材料有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-113796521-A | Health product for old people for supplementing calcium and regulating blood fat and blood pressure and preparation process thereof | 烟台圣莱恩康复医院有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-111233435-A | Glazed ceramic product and preparation method thereof | 德化县宏顺陶瓷有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-110981427-A | Ceramic artwork prepared from waste ceramic and preparation method thereof | 福建省德化佳浩陶瓷有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110885251-A | Green fruit glaze ceramic artwork and preparation method thereof | 福建省德化佳浩陶瓷有限公司 | 2020-03-17 | — | — | CN | claimed |
| US-20030046777-A1 | EMULSION OF WATER SOLUBLE DYES IN A LIPOPHILIC CARRIER | KEE ACTION SPORTS CANADA, INC. (F/K/A AJ ACQUISITION CANADA, INC.) | 2003-03-13 | — | — | US | claimed |
| WO-2003018905-A1 | EMULSION OF WATER SOLUBLE DYES IN A LIPOPHILIC CARRIER | R.P. SCHERER TECHNOLOGIES, INC. (US) | 2003-03-06 | — | — | WO | claimed |
| US-6414066-B1 | BLEND OF THERMOSETTING BINDER AND RESIDUE OF DEPOLYMERIZED NYLON 6 WASTE CARPET | ALLIEDSIGNAL INC. | 2002-07-02 | — | — | US | claimed |
| US-20260014293-A1 | HEMOSTATIC AGENT IN PASTE FORM, USE THEREOF, AND METHOD FOR PRODUCING A LOCAL ACTIVE AGENT RELEASE SYSTEM | HERAEUS MEDICAL GMBH (DE) | 2026-01-15 | — | — | US | disclosed |
| EP-4678196-A1 | PASTY HAEMOSTYPTIC, ITS USE AND A METHOD FOR THE PREPARATION OF A LOCAL DRUG DELIVERY SYSTEM | Heraeus Medical GmbH (DE) | 2026-01-14 | — | — | EP | disclosed |
| CN-119220219-A | Double-component polyurethane elastic structural adhesive suitable for bonding plastic substrates of automobile spoilers and preparation method thereof | 杭州之江有机硅化工有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-0104630-A2 | Animal growth promotant and method of use for animal growth | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-04 | — | — | EP | disclosed |
| US-4352821-A | FRUCTOSE, WATER INSOLUBLE SALT AS CARRIER | SHAKLEE CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| US-4209518-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014293-A1 | HEMOSTATIC AGENT IN PASTE FORM, USE THEREOF, AND METHOD FOR PRODUCING A LOCAL ACTIVE AGENT RELEASE SYSTEM | F9, PLAT, F12 | CA4 2987/4885CA1 3418/4885FAHD1 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.