SCHEMBL5327653

SCHEMBL5327653

O=C(O)C1(CCN2CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.35
TBXAS1 P24557 2/20 0.34
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GLA P06280 1/20 0.32
HRH1 P35367 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
ARG1 P05089 1/20 0.31
PAOX Q6QHF9 1/20 0.31
HTR7 P34969 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5325425 0.85 CYP2C19 (0.45) CYP2C19TBXAS1CYP1A2MAPK1SMN1; SMN2
SCHEMBL6627748 0.79 GLA (0.49) CYP2C19CYP1A2SMN1; SMN2GLAALDH1A1
SCHEMBL5327581 0.76 HRH1 (0.44) CYP2C19HRH1
SCHEMBL7620722 0.76 SIGMAR1 (0.51) SMN1; SMN2ALDH1A1POLBHTR7
SCHEMBL6223421 0.72 HRH1 (0.43) CYP1A2SMN1; SMN2HRH1ALDH1A1PAOX
SCHEMBL25011375 0.71 CYP2C19 (0.36) CYP2C19TBXAS1CYP1A2SMN1; SMN2ALDH1A1
SCHEMBL798204 0.70 TBXAS1 (0.45) CYP2C19TBXAS1
SCHEMBL18549878 0.70
SCHEMBL798344 0.70 TBXAS1 (0.45) CYP2C19TBXAS1
SCHEMBL797992 0.70 TBXAS1 (0.45) CYP2C19TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO disclosed