Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331896 | 0.81 | NPC1 (0.53) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL27771732 | 0.79 | ADORA2A (0.46) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL10020886 | 0.78 | CCR1 (0.58) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL4577045 | 0.78 | NPC1 (0.52) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL30090584 | 0.78 | NPC1 (0.52) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL13878868 | 0.78 | MAPK1 (0.52) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL31175944 | 0.76 | CCR1 (0.55) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL5347477 | 0.76 | CCR1 (0.55) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL5325012 | 0.74 | KDM4E (0.59) | CBFBSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL24363083 | 0.74 | KDM4E (0.54) | CBFBSMN1; SMN2NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |