Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CBFB | Q13951 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14116546 | 0.82 | MPL (0.55) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL4730316 | 0.82 | CBFB (0.50) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL28209756 | 0.82 | CBFB (0.50) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL1206412 | 0.82 | CBFB (0.50) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL6301360 | 0.82 | CBFB (0.50) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL5327675 | 0.81 | CBFB (0.59) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL11272726 | 0.81 | ALOX5AP (0.50) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL996983 | 0.81 | CBFB (0.49) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL16457762 | 0.80 | NPC1 (0.41) | NPC1RAB9AMAPK1SMN1; SMN2CBFB | |
| SCHEMBL4188605 | 0.79 | CBFB (0.69) | CBFBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |