Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344927 | 0.97 | KDM4E (0.52) | KDM4EALDH1A1HRH3SLC6A4NPC1 | |
| SCHEMBL5325274 | 0.92 | KDM4E (0.49) | KDM4EALDH1A1HRH3SLC6A4NPC1 | |
| SCHEMBL5366527 | 0.92 | HRH3 (0.54) | HRH3SLC6A4 | |
| SCHEMBL5321011 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1HRH3SLC6A4NPC1 | |
| SCHEMBL5318727 | 0.91 | HRH3 (0.56) | HRH3SLC6A4 | |
| SCHEMBL5321369 | 0.88 | HRH3 (0.46) | KDM4EALDH1A1HRH3SLC6A4NPC1 | |
| SCHEMBL5339292 | 0.85 | HRH3 (0.57) | HRH3 | |
| SCHEMBL5320367 | 0.85 | HRH3 (0.57) | HRH3 | |
| SCHEMBL5348156 | 0.85 | HRH3 (0.57) | HRH3 | |
| SCHEMBL5325115 | 0.80 | HRH3 (0.49) | HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099423-A1 | 1-PYRROLIDINE INDANE DERIVATIVES AS HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-09-07 | — | — | WO | disclosed |