Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327257 | 0.83 | KDM1A (0.51) | KDM1AKDM4ERAB9ABRD4BRD2 | |
| SCHEMBL4725122 | 0.82 | KDM4E (0.44) | KDM1AKDM4EPTGS2RAB9AERN1 | |
| SCHEMBL4529792 | 0.79 | KDM1A (0.43) | KDM1AKDM4ERAB9AMETAP1LMNA | |
| SCHEMBL4025388 | 0.78 | ALDH1A1 (0.51) | KDM4ERAB9AERN1LMNACYP1A2 | |
| Dipyridyl SCHEMBL28723689 | 0.77 | KDM4E (0.59) | KDM1AKDM4ERAB9AMETAP1LMNA | |
| SCHEMBL6068182 | 0.77 | KDM1A (0.54) | KDM1AKDM4ERAB9ABRD4BRD2 | |
| SCHEMBL30900828 | 0.77 | KDM1A (0.54) | KDM1AKDM4ERAB9ABRD4BRD2 | |
| SCHEMBL20591288 | 0.76 | KDM4E (0.54) | KDM1AKDM4ERAB9ABRD4BRD2 | |
| SCHEMBL15485572 | 0.76 | KDM4E (0.54) | KDM1AKDM4ERAB9ABRD4BRD2 | |
| SCHEMBL31039988 | 0.76 | L3MBTL1 (0.42) | KDM1AKDM4EPTGS2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007123910-A2 | COPPER-MEDIATED FUNCTIONALIZATION OF ARYL C-H BONDS, AND COMPOUNDS RELATED THERETO | BRANDEIS UNIVERSITY (US) | 2007-11-01 | — | — | WO | disclosed |