Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325256 | 0.90 | HTR6 (0.53) | HTR6KLK7CYP3A4ADRA2ACYP2D6 | |
| SCHEMBL5328661 | 0.88 | HTR6 (0.52) | HTR6KLK7CYP3A4ADRA2ACYP2D6 | |
| SCHEMBL5330866 | 0.87 | HTR6 (0.50) | HTR6KLK7CYP3A4CYP2D6 | |
| SCHEMBL5410849 | 0.86 | HTR6 (0.54) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL5328089 | 0.81 | HTR6 (0.54) | HTR6ACLYKLK7 | |
| SCHEMBL5330688 | 0.80 | HTR6 (0.53) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL5414724 | 0.78 | HTR6 (0.52) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL5327029 | 0.77 | HTR6 (0.49) | HTR6KLK7 | |
| SCHEMBL3595920 | 0.75 | HTR6 (0.63) | HTR6 | |
| SCHEMBL27636796 | 0.75 | HTR6 (0.59) | HTR6ACLYCYP3A4ADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |