Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325258 | 0.90 | HTR6 (0.53) | HTR6HTR7KLK7 | |
| SCHEMBL5328664 | 0.88 | HTR6 (0.54) | HTR6HTR7KLK7 | |
| SCHEMBL5330870 | 0.87 | HTR6 (0.52) | HTR6HTR7 | |
| SCHEMBL5410856 | 0.86 | HTR6 (0.55) | HTR6HTR7 | |
| SCHEMBL3595920 | 0.82 | HTR6 (0.63) | HTR6HTR7 | |
| SCHEMBL5328085 | 0.81 | HTR6 (0.52) | HTR6ACLYKLK7 | |
| SCHEMBL3560031 | 0.80 | HTR6 (0.54) | HTR6HTR7ACLY | |
| SCHEMBL5330692 | 0.79 | HTR6 (0.53) | HTR6 | |
| SCHEMBL5414728 | 0.78 | HTR6 (0.62) | HTR6HTR7 | |
| SCHEMBL5327034 | 0.78 | HTR6 (0.49) | HTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |