Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.47 |
| ▸ | PPARA | Q07869 | 16/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183099 | 0.83 | PPARG (0.46) | PPARGPPARASMN1; SMN2LDHA | |
| SCHEMBL27480760 | 0.79 | PPARG (0.46) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL5274970 | 0.79 | SMN1; SMN2 (0.68) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL5405854 | 0.74 | SMN1; SMN2 (0.60) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL21057172 | 0.71 | LDHA (0.58) | PPARGPPARALDHA | |
| SCHEMBL21057169 | 0.71 | LDHA (0.58) | PPARGPPARALDHA | |
| SCHEMBL21057120 | 0.70 | PPARG (0.63) | PPARGPPARASMN1; SMN2LDHA | |
| SCHEMBL21057123 | 0.70 | PPARG (0.63) | PPARGPPARASMN1; SMN2LDHA | |
| SCHEMBL4851925 | 0.70 | PPARG (0.63) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL28551619 | 0.69 | CYP1A2 (0.65) | PPARGPPARASMN1; SMN2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |