Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.46 |
| ▸ | PPARA | Q07869 | 16/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187184 | 0.84 | LDHA (0.61) | PPARGPPARALDHA | |
| SCHEMBL4170587 | 0.83 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL5328247 | 0.83 | PPARG (0.47) | PPARGPPARASMN1; SMN2LDHA | |
| SCHEMBL4173522 | 0.82 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL4180715 | 0.82 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL5274970 | 0.82 | SMN1; SMN2 (0.68) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL27480760 | 0.82 | PPARG (0.46) | PPARGPPARASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18321310 | 0.81 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL5405854 | 0.77 | SMN1; SMN2 (0.60) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL28551619 | 0.72 | CYP1A2 (0.65) | PPARGPPARASMN1; SMN2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | claimed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | claimed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | claimed |
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | OPRL1, OPRK1, AVPR1A | PPARG 2322/4885PPARA 1589/4885SMN1; SMN2 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.