Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324521 | 1.00 | SLC6A4 (0.42) | SLC6A4SLC6A2ADRB1ADRA2AADRB3 | |
| SCHEMBL5330393 | 0.84 | SLC6A2 (0.40) | SLC6A4SLC6A2ADRB1ADRA2AADRB3 | |
| SCHEMBL28778319 | 0.82 | GABBR2 (0.44) | GABBR2GABBR1AOC3 | |
| SCHEMBL7666332 | 0.82 | SLC6A4 (0.47) | SLC6A4SLC6A2TAAR1ALDH1A1HTR1A | |
| SCHEMBL5013017 | 0.82 | SLC6A4 (0.47) | SLC6A4SLC6A2ADRB1ADRA2AADRB3 | |
| SCHEMBL5326905 | 0.81 | ADRA2A (0.46) | SLC6A4SLC6A2ADRB1ADRA2AADRB3 | |
| SCHEMBL1959897 | 0.79 | ESR1 (0.40) | ADRA2AADRA2BADRA2CTDP1GABBR2 | |
| SCHEMBL1834790 | 0.79 | ESR1 (0.40) | ADRA2AADRA2BADRA2CTDP1GABBR2 | |
| SCHEMBL1835662 | 0.79 | ESR1 (0.40) | ADRA2AADRA2BADRA2CTDP1GABBR2 | |
| SCHEMBL5425514 | 0.79 | GRIA4 (0.44) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136323-A1 | A NOVEL PROCESS SUITABLE FOR LARGE-SCALE PRODUCTION OF PHENYL PROPAN DERIVATIVES OF FORMULA I | ALBIREO AB (SE) | 2007-11-29 | — | — | WO | claimed |
| US-20070270487-A1 | Novel process and intermediates 085 | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | claimed |
| WO-2007136323-A1 | A NOVEL PROCESS SUITABLE FOR LARGE-SCALE PRODUCTION OF PHENYL PROPAN DERIVATIVES OF FORMULA I | ALBIREO AB (SE) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007136323-A1 | A NOVEL PROCESS SUITABLE FOR LARGE-SCALE PRODUCTION OF PHENYL PROPAN DERIVATIVES OF FORMULA I | ALBIREO AB (SE) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270487-A1 | Novel process and intermediates 085 | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | disclosed |
| US-20070270487-A1 | Novel process and intermediates 085 | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | disclosed |
| US-20070270487-A1 | Novel process and intermediates 085 | ASTRAZENECA AB (SE) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270487-A1 | Novel process and intermediates 085 | CYP3A5, AGPAT5, CYP4F8 | SLC6A4 2682/4885SLC6A2 3820/4885ADRB1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.