Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440741 | 0.82 | TDP1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL14361137 | 0.81 | HPGD (0.44) | ALDH1A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL30518067 | 0.78 | KMT2A (0.49) | ALDH1A1MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL30518098 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL30518105 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL30518106 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL11228603 | 0.74 | TDP1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL9359182 | 0.73 | KDM4E (0.36) | ALDH1A1MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL29078168 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL29078124 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | YALE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| EP-1745056-A4 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY CORP (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1745056-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | Yale University Corporation (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005111050-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | AKR1C3, PCNA, AKR1C4 | ALDH1A1 1120/4885MEN1 1734/4885KMT2A 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.