Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519413 | 0.93 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL14541002 | 0.93 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL4520297 | 0.92 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Phosphoric Acid SCHEMBL5330246 | 0.91 | HTR1A (0.46) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL5326464 | 0.90 | HTR1A (0.50) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL4532832 | 0.89 | DRD2 (0.45) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL4537655 | 0.88 | HTR1A (0.45) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Succinic Acid SCHEMBL5327789 | 0.88 | DRD2 (0.45) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Phosphoric Acid SCHEMBL5330466 | 0.87 | HTR1A (0.43) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Cadaverine Tartrate SCHEMBL5332836 | 0.87 | DRD2 (0.44) | HTR1ADRD2HTR2AADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039809-A1 | METABOLITES OF 2- {3-[4-(5-FLUORO-2-ISOPROPOXY-PHENYL)-PIPERAZIN-1-YL]-PROPYL} -5,6-DIHYDROXY-HEXAHYDRO-ISOINDOLE-1,3-DIONE | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039809-A1 | METABOLITES OF 2- {3-[4-(5-FLUORO-2-ISOPROPOXY-PHENYL)-PIPERAZIN-1-YL]-PROPYL} -5,6-DIHYDROXY-HEXAHYDRO-ISOINDOLE-1,3-DIONE | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-12 | — | — | WO | disclosed |