Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330302 | 0.89 | MEN1 (0.48) | CNR2CNR1 | |
| SCHEMBL5324532 | 0.81 | THRB (0.65) | THRBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5326974 | 0.81 | THRB (0.49) | THRBCNR2KDM4EALDH1A1HPGD | |
| SCHEMBL5327228 | 0.78 | THRB (0.42) | THRBTHRA | |
| SCHEMBL5398709 | 0.78 | THRB (0.42) | THRBKDM4EALDH1A1MAPTTHRA | |
| SCHEMBL5332095 | 0.77 | THRB (0.63) | THRBALDH1A1HPGDTHRA | |
| SCHEMBL5415371 | 0.76 | THRB (0.45) | THRBKDM4EALDH1A1MAPTALOX12 | |
| SCHEMBL5322895 | 0.75 | THRB (0.40) | THRBTHRA | |
| SCHEMBL5437353 | 0.75 | THRB (0.40) | THRBKDM4EALDH1A1MAPTTHRA | |
| SCHEMBL5329530 | 0.74 | THRB (0.43) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |