SCHEMBL53287

SCHEMBL53287

O=C1c2ccccc2C(=O)N1CCBr

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.63
CES1 P23141 1/20 0.63
GLS O94925 1/20 0.61
RAB9A P51151 3/20 0.53
CASP3 P42574 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAPT P10636 1/20 0.52
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30434337 1.00 BCHE (0.63) BCHECES1GLSRAB9ACASP3
SCHEMBL8722547 0.87 BCHE (0.51) BCHECES1GLSRAB9ACASP3
SCHEMBL29351736 0.87 GLS (0.62) GLSRAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL56978 0.87 GLS (0.62) GLSRAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL6699936 0.85 GLS (0.71) BCHECES1GLSRAB9ACASP3
SCHEMBL29459467 0.85 TDP1 (0.61) GLSRAB9ASMN1; SMN2TDP1L3MBTL1
Hydrochloric Acid SCHEMBL10638625 0.85 GLS (0.60) GLSRAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL14468 0.85 TDP1 (0.61) GLSRAB9ASMN1; SMN2TDP1L3MBTL1
SCHEMBL7515272 0.84 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19
SCHEMBL4579395 0.84 TDP1 (0.64) TDP1L3MBTL1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2916 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
US-20260015354-A1 Solid State Forms of Ensifentrine CIPLA LIMITED (IN) 2026-01-15 US claimed
WO-2024127413-A1 SOLID STATE FORMS OF ENSIFENTRINE CIPLA LIMITED (IN) 2024-06-20 WO claimed
CN-117965248-A Glue removing liquid for OLED flexible panel 江苏中德电子材料科技有限公司 2024-05-03 CN claimed
CN-116858908-A Highly stable carbene-alkynyl probe molecule self-assembly interface and preparation method and application thereof 华东师范大学 2023-10-10 CN claimed
CN-113295667-B Detect Cu simultaneously + And Cu 2+ Surface-enhanced Raman spectrum probe and preparation method and application thereof 华东师范大学 2022-12-06 CN claimed
CN-114702479-A Preparation method of furfural-based color-changing dye 四川大学 2022-07-05 CN claimed
CN-113295667-A Detect Cu simultaneously+And Cu2+Surface-enhanced Raman spectrum probe and preparation method and application thereof 华东师范大学 2021-08-24 CN claimed
CN-109020955-B Molecular probe, preparation method and application thereof 深圳大学 2021-08-17 CN claimed
CN-113173891-A Molecular probe derived from calcium-sensitive receptor protein antagonist and application of molecular probe in parathyroidectomy 大连医科大学附属第二医院 2021-07-27 CN claimed
CN-106008506-B Substituted purin analog derivative and preparation method and application 山东大学 2018-02-13 CN claimed
CN-106008506-A Substituted purine derivative and preparation method and application thereof 山东大学 2016-10-12 CN claimed
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0323148-A1 Dopamine-beta-hydroxylase inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1989-07-05 EP claimed