Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295240 | 0.78 | KDM1A (0.44) | KDM1AMAOAMAOBSLC6A2SLC6A4 | |
| SCHEMBL31143852 | 0.76 | KDM1A (0.43) | KDM1AMAOAMAOB | |
| SCHEMBL503776 | 0.75 | KDM1A (0.42) | KDM1AMAOAMAOBOPRM1SLC6A2 | |
| SCHEMBL6735371 | 0.75 | KDM1A (0.42) | KDM1AMAOAMAOBSLC6A2SLC6A4 | |
| SCHEMBL29209554 | 0.75 | KDM1A (0.42) | KDM1AMAOAMAOBSLC6A2SLC6A4 | |
| SCHEMBL2481698 | 0.75 | KDM1A (0.59) | KDM1AMAOAMAOB | |
| SCHEMBL1248050 | 0.75 | KDM1A (0.44) | KDM1AMAOAMAOBSLC6A2SLC6A4 | |
| SCHEMBL1535881 | 0.75 | SLC6A9 (0.43) | KDM1AMAOAMAOBOPRM1SLC6A9 | |
| SCHEMBL8720460 | 0.75 | KDM1A (0.42) | KDM1AMAOAMAOBSLC6A9 | |
| SCHEMBL2791867 | 0.75 | AKR1C1 (0.43) | KDM1AMAOAMAOBAKR1C1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4014231-B2 | — | — | 2007-11-28 | — | — | JP | claimed |
| JP-2002511060-A | — | — | 2002-04-09 | — | — | JP | claimed |
| EP-1021452-A1 | PROCESS FOR SYNTHESIZING PHOSPHODIESTERS | Epix Medical, Inc. (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1998046612-A1 | PROCESS FOR SYNTHESIZING PHOSPHODIESTERS | EPIX MEDICAL, INC. (US) | 1998-10-22 | — | — | WO | claimed |