Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506314 | 0.81 | L3MBTL1 (0.65) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL5323040 | 0.81 | L3MBTL1 (0.65) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL29091640 | 0.78 | CES1 (0.41) | DAOCES1NSD2BCHEL3MBTL1 | |
| Water SCHEMBL8678456 | 0.77 | DDB1 (0.45) | DAOPTPRCGRK6TTRCASP3 | |
| SCHEMBL31016514 | 0.77 | CES1 (0.54) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL31244383 | 0.75 | DAO (0.53) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL31244371 | 0.75 | DAO (0.53) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL951019 | 0.75 | DAO (0.61) | DAOCES1NSD2BCHEL3MBTL1 | |
| SCHEMBL7399139 | 0.75 | DDB1 (0.46) | DAOPTPRCGRK6TTRCASP3 | |
| SCHEMBL3063162 | 0.73 | CES1 (0.58) | DAOCES1NSD2BCHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132280-A1 | ISATIN AND ITS DERIVATIVES FOR USE AS A MEDICAMENT | Szegedi Tudományegyetem (HU) | 2007-11-22 | — | — | WO | disclosed |