Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8678456 | 0.98 | DDB1 (0.45) | DDB1CRBNMEN1KMT2APDK2 | |
| SCHEMBL7648225 | 0.87 | CYP2A6 (0.43) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL4593117 | 0.83 | PRKCA (0.45) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL2701829 | 0.83 | GSK3B (0.42) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL11400171 | 0.82 | CASP3 (0.37) | DDB1CRBNMEN1KMT2APDK2 | |
| SCHEMBL28095488 | 0.82 | PARP1 (0.53) | DDB1CRBNMEN1KMT2APDK2 | |
| SCHEMBL10628503 | 0.81 | ALDH1A1 (0.36) | DDB1CRBNMEN1KMT2ACHEK1 | |
| SCHEMBL9768590 | 0.80 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL384815 | 0.80 | TOP1 (0.55) | MEN1KMT2ACHEK1WEE1KDM4E | |
| SCHEMBL29378366 | 0.80 | TOP1 (0.55) | MEN1KMT2ACHEK1WEE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749187-B | A kind of synthetic method of phthalyl Amlodipine | 千辉药业（安徽）有限责任公司 | 2019-07-05 | — | — | CN | claimed |
| CN-107983310-A | Hydrophobic charge-induction chromatography medium with bifunctional group | 苏州博进生物技术有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107935912-A | A kind of preparation process of Amlodipine intermediate | 常州瑞明药业有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-106749187-A | A kind of synthetic method of phthalyl Amlodipine | 千辉药业（安徽）有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| CN-107936953-B | A kind of fluorescence probe and its preparation method and application | 深圳先进技术研究院 | 2019-10-11 | — | — | CN | disclosed |
| CN-106749187-B | A kind of synthetic method of phthalyl Amlodipine | 千辉药业（安徽）有限责任公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106749187-B | A kind of synthetic method of phthalyl Amlodipine | 千辉药业（安徽）有限责任公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109651208-A | N- arylsulfonamides compound, medical composition and its use | 中国科学院上海药物研究所 | 2019-04-19 | — | — | CN | disclosed |
| CN-109326502-A | Semiconductor device and method | 台湾积体电路制造股份有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-107983310-A | Hydrophobic charge-induction chromatography medium with bifunctional group | 苏州博进生物技术有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107935912-A | A kind of preparation process of Amlodipine intermediate | 常州瑞明药业有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107935912-A | A kind of preparation process of Amlodipine intermediate | 常州瑞明药业有限公司 | 2018-04-20 | — | — | CN | disclosed |
| EP-0818512-B1 | Quinoline derivative and use of same | MITSUI CHEMICALS INC (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6407242-B1 | REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE | MITSUI CHEMICALS, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995025090-A1 | CYCLIC N-ALKENYLOXYIMIDES AND A METHOD FOR THE PREPARATION OF CYCLIC N-ALKENYLOXYIMIDES, THE CORRESPONDING CYCLIC N-ALKOXYIMIDES AND O-ALKOXYAMINES | DSM N.V. (NL) | 1995-09-21 | — | — | WO | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |
| WO-1993017034-A1 | AMPHOTERICIN B DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | disclosed |