Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933571 | 0.73 | HDAC6 (0.72) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5334232 | 0.72 | ALPL (0.59) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL13856738 | 0.72 | MAPT (0.85) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL13856737 | 0.72 | MAPT (1.00) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL13649430 | 0.72 | HDAC6 (0.61) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL757031 | 0.71 | RAB9A (0.62) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL30037937 | 0.71 | RAB9A (0.62) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL7018296 | 0.70 | RAB9A (0.58) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10035832 | 0.70 | HDAC6 (0.58) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL1167938 | 0.69 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |