Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682489 | 0.91 | KDM4E (0.64) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL1154123 | 0.89 | DNMT3A (0.66) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL5323204 | 0.88 | PPARA (0.58) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL1154002 | 0.87 | DNMT3A (0.60) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL14398029 | 0.87 | MAPT (0.61) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL3687774 | 0.86 | DNMT3A (0.69) | KDM4EALDH1A1PKMSMN1; SMN2PPARA | |
| SCHEMBL14397668 | 0.86 | PPARA (0.59) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL5321712 | 0.84 | DNMT3A (0.69) | MAPTSMN1; SMN2PPARAPPARGNR1H4 | |
| SCHEMBL11683949 | 0.84 | KDM4E (0.58) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL5329406 | 0.84 | PPARA (0.54) | KDM4EMAPTALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |