Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | FABP2 | P12104 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323204 | 0.89 | PPARA (0.58) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL6363486 | 0.89 | ALDH1A1 (0.58) | PPARAALDH1A1PPARDSMN1; SMN2MAPT | |
| SCHEMBL3687774 | 0.88 | DNMT3A (0.69) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL5329406 | 0.86 | PPARA (0.54) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL5329484 | 0.86 | KDM4E (0.64) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL1154123 | 0.85 | DNMT3A (0.66) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL14398029 | 0.84 | MAPT (0.61) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL11682489 | 0.82 | KDM4E (0.64) | PPARAALDH1A1PPARDFABP2PPARG | |
| SCHEMBL14397757 | 0.82 | ALDH1A1 (0.43) | PPARAALDH1A1PPARDPPARGMEN1 | |
| SCHEMBL1153879 | 0.80 | ALDH1A1 (0.58) | PPARAALDH1A1PPARDFABP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |