Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619767 | 0.85 | NR4A2 (0.48) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL7033458 | 0.85 | NR4A2 (0.48) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL7034582 | 0.84 | CA1 (0.57) | NR4A2CA1CA2CA5ACA9 | |
| Chlorobenzene SCHEMBL27316569 | 0.80 | SLC6A3 (0.50) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL7030212 | 0.78 | NR4A2 (0.42) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL10986337 | 0.78 | CA1 (0.51) | CA1CA2CA5ACA9LMNA | |
| SCHEMBL917144 | 0.76 | NR4A2 (0.51) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL27542799 | 0.76 | CA1 (0.54) | NR4A2CA1CA2CA5ACA9 | |
| SCHEMBL993113 | 0.75 | TSHR (0.59) | NR4A2LMNATSHRSLC6A4SLC6A3 | |
| SCHEMBL433518 | 0.75 | CA1 (0.53) | CA1CA2CA5ACA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |