Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548319 | 0.91 | F10 (0.58) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548407 | 0.87 | F10 (0.60) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL5329388 | 0.87 | F10 (0.49) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548437 | 0.87 | F10 (0.49) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548419 | 0.84 | F10 (0.63) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL29625940 | 0.80 | F10 (0.76) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL28757174 | 0.80 | F10 (0.76) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL27639305 | 0.79 | F10 (0.57) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL65730 | 0.79 | F10 (0.77) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7479169 | 0.78 | F10 (0.71) | F10TPSAB1PRSS1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041593-A2 | ANTI-SCARRING DRUG COMBINATIONS AND USE THEREOF | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041584-A2 | IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |