Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649014 | 0.80 | CA1 (0.48) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL5332535 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL14346341 | 0.80 | CA1 (0.48) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL5362566 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL5325413 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL5325574 | 0.75 | TP53 (0.53) | LMNATP53MEN1KMT2A | |
| SCHEMBL5331465 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL5333492 | 0.74 | HTR2B (0.51) | KDM4EALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL5328078 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL5324855 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1MAPTTP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146230-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-12-21 | — | — | WO | claimed |