Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 8/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325835 | 0.93 | MAPT (0.42) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5326162 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5329767 | 0.89 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5325121 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5326617 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5321455 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5328167 | 0.88 | MAPT (0.44) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5330027 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5415056 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1MAPTL3MBTL1BCHELMNA | |
| SCHEMBL5389491 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1BCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |