Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.56 |
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407869 | 0.94 | PTGDR2 (0.54) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5328966 | 0.92 | PTGDR2 (0.55) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5328560 | 0.90 | HTR6 (0.48) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5425733 | 0.88 | PTGDR2 (0.58) | PTGDR2PTGDRHTR6 | |
| SCHEMBL5331494 | 0.88 | HTR6 (0.50) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5325375 | 0.87 | HTR6 (0.50) | PTGDR2PTGDRHTR6HTR1ADRD2 | |
| SCHEMBL5336640 | 0.87 | HTR6 (0.50) | PTGDR2PTGDRHTR6HTR1ADRD2 | |
| SCHEMBL5328058 | 0.86 | HTR6 (0.49) | PTGDR2PTGDRHTR6HTR1ADRD2 | |
| SCHEMBL5420518 | 0.85 | PTGDR2 (0.45) | PTGDR2PTGDRHTR6 | |
| SCHEMBL5402340 | 0.85 | PTGDR2 (0.40) | PTGDR2PTGDRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |