Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331545 | 0.91 | HTR6 (0.51) | HTR6ALDH3A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5327669 | 0.89 | HTR6 (0.45) | HTR6HDAC1HDAC2HDAC6HTR1A | |
| SCHEMBL5407869 | 0.89 | PTGDR2 (0.54) | HTR6PTGDR2PTGDR | |
| SCHEMBL5326312 | 0.87 | NOD1 (0.42) | HTR6HDAC1HDAC2HDAC6NOD1 | |
| SCHEMBL5331879 | 0.87 | HTR6 (0.55) | HTR6PTGDR2PTGDRHDAC1HDAC2 | |
| SCHEMBL5329968 | 0.87 | PTGDR2 (0.56) | HTR6PTGDR2PTGDRHTR1ADRD2 | |
| SCHEMBL5420518 | 0.85 | PTGDR2 (0.45) | HTR6PTGDR2PTGDR | |
| SCHEMBL5328966 | 0.85 | PTGDR2 (0.55) | HTR6PTGDR2PTGDR | |
| SCHEMBL5327666 | 0.85 | HTR6 (0.48) | HTR6HDAC1HDAC2HDAC6 | |
| SCHEMBL5330910 | 0.84 | HTR6 (0.51) | HTR6PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |