Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1D known ✓ | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1B known ✓ | P35368 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 10/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 6/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528194 | 0.96 | HTR1A (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL4538409 | 0.96 | HTR1A (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Phosphoric Acid SCHEMBL5331722 | 0.95 | HTR1A (0.42) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Phosphoric Acid SCHEMBL5303116 | 0.93 | HTR1A (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5329995 | 0.92 | HTR1A (0.41) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Succinic Acid SCHEMBL5327837 | 0.92 | HTR1A (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL4532644 | 0.91 | HTR1A (0.44) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Fumaric Acid SCHEMBL5329491 | 0.91 | HTR1A (0.44) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Cadaverine Tartrate SCHEMBL5329934 | 0.91 | HTR1A (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Maleic Acid SCHEMBL5329485 | 0.91 | HTR1A (0.44) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010504-A2 | ACID ADDITION SALTS OF ISOINDOLES ACTING AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-25 | — | — | WO | disclosed |