Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557447 | 0.92 | PTK2B (0.61) | PTK2BTSHRALDH1A1HTTKMT2A | |
| SCHEMBL3555144 | 0.88 | PTK2B (0.57) | PTK2BTSHRALDH1A1HTTKMT2A | |
| SCHEMBL28261321 | 0.86 | ALDH1A1 (0.62) | PTK2BTSHRALDH1A1KMT2AGAA | |
| SCHEMBL7163015 | 0.85 | ALDH1A1 (0.68) | PTK2BALDH1A1KMT2AGAATDP1 | |
| SCHEMBL2825153 | 0.84 | MEN1 (0.61) | PTK2BALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL4816354 | 0.82 | ALDH1A1 (0.55) | PTK2BTSHRALDH1A1KMT2AGAA | |
| SCHEMBL15713386 | 0.82 | PTK2B (0.59) | PTK2BTSHRALDH1A1HTTGAA | |
| SCHEMBL3718775 | 0.81 | TSHR (0.65) | PTK2BTSHRALDH1A1HTTKMT2A | |
| SCHEMBL3560143 | 0.81 | PTK2B (0.58) | PTK2BTSHRALDH1A1KMT2AKAT6A | |
| SCHEMBL3563292 | 0.81 | PTK2B (0.58) | PTK2BTSHRALDH1A1KMT2AFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |