Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379280 | 0.87 | FAAH (0.48) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL5074173 | 0.87 | FAAH (0.48) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL5076175 | 0.87 | FAAH (0.48) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL6528747 | 0.85 | ALDH1A1 (0.48) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL7858045 | 0.83 | NPC1 (0.52) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL3051205 | 0.83 | NPC1 (0.46) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL5384233 | 0.80 | FAAH (0.50) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL5381734 | 0.80 | FAAH (0.50) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL8957643 | 0.80 | FAAH (0.50) | CA2FAAHALDH1A1NPC1S1PR2 | |
| SCHEMBL10587430 | 0.80 | FAAH (0.50) | CA2FAAHALDH1A1NPC1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143735-A2 | POLYCATIONIC SULFONAMIDES AND USE THEREOF | THE UNIVERSITY OF KANSAS (US) | 2007-12-13 | — | — | WO | disclosed |