Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1834220 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL935169 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL7113110 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL27268728 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL5313883 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL1551352 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL30610433 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL12521001 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDCLK4KCNA5 | |
| SCHEMBL5700281 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1TDP1PDE3BPDE3A | |
| SCHEMBL14525860 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HPGDCLK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141529-A1 | FLUORIDATION METHOD | GE HEALTHCARE LIMITED (GB) | 2007-12-13 | — | — | WO | disclosed |