Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 13/20 | 0.46 |
| ▸ | ABCC5 | O15440 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 2/20 | 0.46 |
| ▸ | PDE9A | O76083 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE6C | P51160 | 2/20 | 0.46 |
| ▸ | PDE1A | P54750 | 2/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | PDE8A | O60658 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5355292 | 0.99 | KMT2A (0.56) | KMT2AKDM4ECA12CA9CA1 | |
| Hydrochloric Acid SCHEMBL5365443 | 0.90 | KMT2A (0.56) | KMT2AKDM4ECA12CA9CA1 | |
| SCHEMBL6104644 | 0.87 | PDE5A (0.49) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| Hydrochloric Acid SCHEMBL5326033 | 0.86 | PDE5A (0.48) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL6101530 | 0.80 | ABCG2 (0.43) | KMT2APDE5AHDAC1HDAC6 | |
| SCHEMBL5324992 | 0.79 | TUBB4A (0.48) | KMT2APDE5A | |
| Hydrochloric Acid SCHEMBL6103364 | 0.79 | ABCG2 (0.42) | KMT2APDE5AHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL5369434 | 0.78 | TUBB4A (0.47) | KMT2APDE5A | |
| SCHEMBL6103594 | 0.78 | PDE5A (0.49) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| Hydrochloric Acid SCHEMBL5324056 | 0.78 | BCL6 (0.44) | KMT2APDE5AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814885-A2 | NOVEL BICYCLIC HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006073610-A2 | NOVEL BICYCLIC HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | claimed |
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | HPSE, ENGASE, UGCG | KMT2A 4076/4885KDM4E 2836/4885CA12 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.