Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 13/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE6C | P51160 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5326033 | 0.99 | PDE5A (0.48) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6103594 | 0.91 | PDE5A (0.49) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5361577 | 0.90 | PDE5A (0.49) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5324992 | 0.87 | TUBB4A (0.48) | PDE5AKMT2AALDH1A1MAPTBCL6 | |
| SCHEMBL5330304 | 0.87 | KMT2A (0.56) | PDE5AKMT2APDE1APDE1BPDE1C | |
| Hydrochloric Acid SCHEMBL5369434 | 0.86 | TUBB4A (0.47) | PDE5AKMT2AALDH1A1MAPTBCL6 | |
| Hydrochloric Acid SCHEMBL5355292 | 0.86 | KMT2A (0.56) | PDE5AKMT2APDE1APDE1BPDE1C | |
| Hydrochloric Acid SCHEMBL5324056 | 0.85 | BCL6 (0.44) | PDE5AKMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL6101530 | 0.84 | ABCG2 (0.43) | PDE5AKMT2AMEN1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL6103364 | 0.84 | ABCG2 (0.42) | PDE5AKMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | HPSE, ENGASE, UGCG | PDE5A 3544/4885KMT2A 4076/4885MEN1 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.