SCHEMBL5330308

SCHEMBL5330308

CCC(N)C(=O)OC(C)C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
LMNA P02545 2/20 0.38
SLC1A3 P43003 2/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
SLC7A5 Q01650 1/20 0.34
ALOX15 P16050 2/20 0.33
HCAR2 Q8TDS4 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
LAP3 P28838 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SLC15A1 P46059 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30606392 1.00 TSHR (0.40) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL13155620 1.00 TSHR (0.40) TSHRLMNASLC1A3SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL10347009 0.98 TSHR (0.39) TSHRLMNASLC1A3SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL17005230 0.98 TSHR (0.39) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL10205198 0.82 SLC1A2 (0.39) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL15075211 0.82 SLC1A2 (0.39) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL4534790 0.81 TSHR (0.40) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL2494007 0.81 TSHR (0.40) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL27621457 0.81 TSHR (0.40) TSHRLMNASLC1A3SLC1A2SLC1A1
SCHEMBL26276763 0.81 SLC1A3 (0.35) SLC1A3SLC1A2SLC1A1SLC7A5ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109251163-A A kind of method for splitting of indoline -2- formic acid compound and wherein mesosome 江苏永达药业有限公司 2019-01-22 CN claimed
US-20250215465-A1 ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) 2025-07-03 US disclosed
EP-4493708-A1 ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES University of the Witwatersrand, Johannesburg (ZA) 2025-01-22 EP disclosed
CN-118974266-A Enantioselective process for preparing chiral amine intermediates 约翰内斯堡威特沃特斯兰德大学 2024-11-15 CN disclosed
CN-117534629-A Triazinone compound and preparation method and application thereof 贵州大学 2024-02-09 CN disclosed
WO-2023197017-A1 ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) 2023-10-12 WO disclosed
EP-3102215-B1 4'-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF INFLUENZA RNA REPLICATION RIBOSCIENCE LLC (US) 2021-06-16 EP disclosed
WO-2019030387-A1 SOLID COMPOSITION COMPRISING AMORPHOUS SOFOSBUVIR AND AMORPHOUS DACLATASVIR SANDOZ AG (CH) 2019-02-14 WO disclosed
CN-109251163-A A kind of method for splitting of indoline -2- formic acid compound and wherein mesosome 江苏永达药业有限公司 2019-01-22 CN disclosed
EP-2890704-B1 2'-ETHYNYL NUCLEOSIDE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS NOVARTIS AG (CH) 2018-02-28 EP disclosed
US-20090197835-A1 VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2009-08-06 US disclosed
US-20080318901-A1 Novel Lysophosphatidic Acid Receptor Selective Antagonists UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-12-25 US disclosed
US-20080318901-A1 Novel Lysophosphatidic Acid Receptor Selective Antagonists UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-12-25 US disclosed
WO-2008014286-A1 VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-01-31 WO disclosed
EP-1677791-A4 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL (JP) 2007-08-15 EP disclosed
US-20070088002-A1 Orally available sphingosine 1-phosphate receptor agonists and antagonists NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-04-19 US disclosed
US-20070088002-A1 Orally available sphingosine 1-phosphate receptor agonists and antagonists NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-04-19 US disclosed
EP-1677791-A2 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS Takeda Pharmaceutical Company Limited (JP) 2006-07-12 EP disclosed
WO-2005044793-A2 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 WO disclosed
US-3979457-A ACYLASE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088002-A1 Orally available sphingosine 1-phosphate receptor agonists and antagonists S1PR3, S1PR1, S1PR5 TSHR 232/4885LMNA 2126/4885SLC1A3 1190/4885
US-20090197835-A1 VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS LPAR1, LPAR4, LPAR5 TSHR 509/4885LMNA 2213/4885SLC1A3 2841/4885
US-20250215465-A1 ENANTIOSELECTIVE METHODS FOR PREPARING CHIRAL AMINE INTERMEDIATES BCAT1, BCAT2, CES1 TSHR 1369/4885LMNA 1726/4885SLC1A3 163/4885
US-20080318901-A1 Novel Lysophosphatidic Acid Receptor Selective Antagonists LPAR3, LPAR2, LPAR1 TSHR 475/4885LMNA 2765/4885SLC1A3 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.