Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5330382 | 0.99 | KMT2A (0.41) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| SCHEMBL5332651 | 0.92 | ALDH1A1 (0.38) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| SCHEMBL5328122 | 0.92 | IDO1 (0.40) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5333141 | 0.91 | ALDH1A1 (0.37) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5333618 | 0.91 | IDO1 (0.39) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| SCHEMBL5326124 | 0.91 | IDO1 (0.39) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5330327 | 0.90 | IDO1 (0.39) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| SCHEMBL8226836 | 0.88 | KMT2A (0.36) | KMT2AMAPTIDO1TDO2ALDH1A1 | |
| SCHEMBL5327371 | 0.87 | SMN1; SMN2 (0.42) | KMT2AMAPTIDO1ALDH1A1MEN1 | |
| SCHEMBL14340781 | 0.86 | ATP4A (0.39) | KMT2AIDO1TDO2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299113-A1 | Metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | US | claimed |
| WO-2007148113-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | WO | claimed |
| US-20070299113-A1 | Metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | US | disclosed |
| US-20070299113-A1 | Metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | US | disclosed |
| US-20070299113-A1 | Metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | US | disclosed |
| WO-2007148113-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299113-A1 | Metabotropic glutamate receptor modulators | GRM1, GRM2, GRM3 | KMT2A 1294/4885MAPT 794/4885IDO1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.