Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 7/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795144 | 0.85 | DAO (0.51) | KDM4EDAOIDO1FLT3NR3C1 | |
| SCHEMBL864817 | 0.84 | PCSK9 (0.56) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL11159355 | 0.81 | KDM4E (0.47) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL7896456 | 0.81 | LOXL2 (0.62) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL187518 | 0.81 | KDM4E (0.47) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL3838663 | 0.79 | TSHR (0.58) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL7161852 | 0.78 | FLT3 (0.52) | FLT3RHEB | |
| SCHEMBL27885412 | 0.78 | PCSK9 (0.45) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL11811160 | 0.78 | IDO1 (0.49) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL2826552 | 0.78 | GHSR (0.49) | KDM4EPDPK1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171040-A | Dihydrofuropyran/pyridoindole derivatives and synthesis method thereof | 常州大学 | 2020-05-19 | — | — | CN | claimed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | claimed |
| WO-2025077825-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS | FAUNA BIO INCORPORATED (US) | 2025-04-17 | — | — | WO | disclosed |
| CN-113474340-B | Novel isoindolinone substituted indoles and derivatives as RAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-3931188-B1 | NEW ISOINDOLINONE SUBSTITUTED INDOLES AND DERIVATIVES AS RAS INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-08-30 | — | — | EP | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |
| US-20220144810-A1 | NEW ISOINDOLINONE SUBSTITUTED INDOLES AND DERIVATIVES AS RAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-12 | — | — | US | disclosed |
| EP-2714667-B1 | AMINOOXAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | DESAI LAXMAN S (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-2714667-B1 | AMINOOXAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | DESAI LAXMAN S (US) | 2020-11-25 | — | — | EP | disclosed |
| CN-111171040-A | Dihydrofuropyran/pyridoindole derivatives and synthesis method thereof | 常州大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |
| US-8546400-B2 | 1,3-Oxazole-4-carboxamides, 1,3-Thiazole-4-carboxamides, and 1,3-Imidazole-d-carboxamides as Inhibitors of cyclin Dependent kinases | Neosome Life Sciences, LLC (US) | 2013-10-01 | — | — | US | disclosed |
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2013-07-18 | — | — | US | disclosed |
| WO-2012166463-A2 | AMINOOXAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | Neosome Life Sciences, LLC (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | CDK1, CCNK, CCNI | KDM4E 324/4885PDPK1 210/4885ALDH1A1 2461/4885 |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | CDK1, CCNK, CCNI | KDM4E 324/4885PDPK1 210/4885ALDH1A1 2461/4885 |
| US-20220144810-A1 | NEW ISOINDOLINONE SUBSTITUTED INDOLES AND DERIVATIVES AS RAS INHIBITORS | NRAS, RASSF5, KRAS | KDM4E 3450/4885PDPK1 1483/4885ALDH1A1 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.